簡(jiǎn)介:Miglustat hydrochloride是葡萄糖神經(jīng)酰胺合成酶抑制劑,可作用于I型戈謝病。
Miglustat hydrochloride物理化學(xué)性質(zhì):
沸點(diǎn) |
421.2oC at 760 mmHg |
熔點(diǎn) |
169-172oC |
分子式 |
C10H22ClNO4 |
分子量 |
255.739 |
閃點(diǎn) |
208.5oC |
精確質(zhì)量 |
255.1237 |
PSA |
84.16 |
蒸汽壓 |
7.37E-09mmHg at 25°C |
Miglustat hydrochloride詳細(xì)介紹:
中文名稱: |
N-丁基脫氧野艽霉素鹽酸鹽 |
中文別名: |
N-丁基脫氧野艽霉素鹽酸鹽 |
英文名稱: |
Miglustat hydrochloride |
英文別名: |
N-Butyldeoxynojirimycin Hydrochloride;Miglustat hydrochloride;Miglustat hydrochloride,(2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)-3,4,5-piperidinetriolhydrochloride;NB-DNJ hydrochloride;OGT918 hydrochloride;Miglustat (hydrochloride);N-Butyldeoxynojirimycin, Hydrochloride;N-Butyl-DNJ, HCl;NB-DNJ, HCl;N-Butyldeoxynojirimycin.HCl;SMR000058560;MLS000069516;N-(N-BUTYL)DEOXYNOJIRIMYCIN, HYDROCHLORIDE;(2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride;Miglustat HCl;Opera_ID_475;N-Butyldeoxynojirimycin HCl;C10H21NO4.ClH;OR9100T |
CAS號(hào): |
210110-90-0 |
分子式: |
C10NO4CLH22 |
分子量: |
255.74 |
詳細(xì)描述 |
博飛美科提供210110-90-0,Miglustat hydrochloride,Medlife,上?,F(xiàn)貨。 Medlife,致力于提供高品質(zhì)、高性價(jià)比小分子化合物的產(chǎn)品。 Medlife小分子化合物大量庫(kù)存,提供超過2萬種的抑制劑、激動(dòng)劑、拮抗劑等產(chǎn)品,是藥物及疾病研究的重要原料供應(yīng)商。 葡萄糖神經(jīng)酰胺合酶抑制劑,Miglustat鹽酸鹽是葡萄糖神經(jīng)酰胺合成酶抑制劑,可作用于I型戈謝病。 查詢關(guān)鍵詞:“210110-90-0,Miglustat hydrochloride,PC14966,Medlife,上?,F(xiàn)貨”。 |
Miglustat hydrochloride參考文獻(xiàn):
[1]. Abian, O., et al., Therapeutic strategies for Gaucher disease: miglustat (NB-DNJ) as a pharmacological chaperone for glucocerebrosidase and the different thermostability of velaglucerase alfa and imiglucerase. Mol Pharm, 2011. 8(6): p. 2390-7.
[2]. van Giersbergen, P.L. and J. Dingemanse, Influence of food intake on the pharmacokinetics of miglustat, an inhibitor of glucosylceramide synthase. J Clin Pharmacol, 2007. 47(10): p. 1277-82.
產(chǎn)品技術(shù)規(guī)格說明書由上海創(chuàng)賽科技有限公司收集整理,僅作參考使用。