細胞培養(yǎng)與擴增 | Cell Culture and Expansion
三維細胞培養(yǎng) | 3D Cell Culture
基質(zhì)膠提供了類似于細胞外基質(zhì)(ECM)的環(huán)境,使得細胞能夠在三維空間中生長和擴展。這對于研究細胞行為、分化和相互作用非常重要。
Matrigel provides an ECM-like environment, allowing cells to grow and expand in three dimensions. This is crucial for studying cell behavior, differentiation, and interactions.
干細胞培養(yǎng) | Stem Cell Culture
基質(zhì)膠支持干細胞的生長和多能性保持,是干細胞培養(yǎng)的重要材料。特別是在胚胎干細胞和誘導多能干細胞的培養(yǎng)中,被廣泛使用。
Matrigel supports the growth and maintenance of stem cells' pluripotency, making it an essential material for stem cell culture. It is widely used for culturing embryonic stem cells and induced pluripotent stem cells.
細胞分化與誘導 | Cell Differentiation and Induction
組織特異性分化 | Tissue-Specific Differentiation
基質(zhì)膠可以通過模擬體內(nèi)的微環(huán)境,誘導干細胞分化為特定的細胞類型,如神經(jīng)細胞、肌肉細胞和肝細胞等。
Matrigel can simulate the in vivo microenvironment to induce stem cells to differentiate into specific cell types, such as neurons, muscle cells, and hepatocytes.
器官類器官培養(yǎng) | Organoid Culture
基質(zhì)膠用于培養(yǎng)類器官(organoids),這些三維細胞團能夠模擬真實器官的結(jié)構(gòu)和功能,適用于發(fā)育生物學和疾病模型研究。
Matrigel is used to culture organoids, three-dimensional cell clusters that can mimic the structure and function of real organs, suitable for developmental biology and disease modeling.
腫瘤研究 | Cancer Research
腫瘤模型構(gòu)建 | Tumor Model Construction
基質(zhì)膠常用于構(gòu)建體外腫瘤模型,研究腫瘤細胞的增殖、侵襲和轉(zhuǎn)移機制。
Matrigel is often used to construct in vitro tumor models to study the proliferation, invasion, and metastasis mechanisms of cancer cells.
藥物篩選 | Drug Screening
基質(zhì)膠提供的三維培養(yǎng)環(huán)境可以更真實地模擬體內(nèi)腫瘤微環(huán)境,用于高通量藥物篩選和抗腫瘤藥物的療效評估。
The 3D culture environment provided by Matrigel can more realistically simulate the in vivo tumor microenvironment, used for high-throughput drug screening and efficacy evaluation of anti-cancer drugs.
細胞遷移和侵襲研究 | Cell Migration and Invasion Studies
遷移實驗 | Migration Assays
基質(zhì)膠用于細胞遷移和侵襲實驗,如劃痕實驗和Boyden小室實驗,研究細胞在三維基質(zhì)中的運動行為。
Matrigel is used in cell migration and invasion assays, such as scratch assays and Boyden chamber assays, to study cell movement behavior in a 3D matrix.
侵襲實驗 | Invasion Assays
通過模擬基質(zhì)屏障,研究細胞尤其是腫瘤細胞的侵襲能力和機制。
By simulating the matrix barrier, Matrigel is used to study the invasion capabilities and mechanisms of cells, particularly cancer cells.
血管生成研究 | Angiogenesis Research
血管生成模型 | Angiogenesis Models
基質(zhì)膠可以支持內(nèi)皮細胞在三維環(huán)境中形成血管樣結(jié)構(gòu),用于研究血管生成機制和新型抗血管生成藥物的篩選。
Matrigel can support the formation of blood vessel-like structures by endothelial cells in a 3D environment, used to study angiogenesis mechanisms and screen new anti-angiogenic drugs.
再生醫(yī)學與組織工程 | Regenerative Medicine and Tissue Engineering
組織修復(fù)與再生 | Tissue Repair and Regeneration
基質(zhì)膠在再生醫(yī)學中用于支持細胞移植和組織修復(fù),如皮膚、骨骼和神經(jīng)等組織的再生。
Matrigel is used in regenerative medicine to support cell transplantation and tissue repair, such as the regeneration of skin, bone, and nerve tissues.
生物打印 | Bioprinting
基質(zhì)膠作為生物墨水中的重要成分,用于三維生物打印技術(shù),構(gòu)建復(fù)雜的組織和器官結(jié)構(gòu)。
Matrigel serves as an important component of bio-ink in 3D bioprinting technology, used to construct complex tissue and organ structures.
神經(jīng)生物學研究 | Neurobiology Research
神經(jīng)細胞培養(yǎng) | Neuronal Cell Culture
基質(zhì)膠用于神經(jīng)細胞和神經(jīng)祖細胞的培養(yǎng)和分化研究,模擬神經(jīng)組織的微環(huán)境。
Matrigel is used for the culture and differentiation of neuronal cells and neural progenitor cells, simulating the neural tissue microenvironment.
神經(jīng)網(wǎng)絡(luò)形成 | Neuronal Network Formation
在基質(zhì)膠中培養(yǎng)的神經(jīng)細胞可以形成復(fù)雜的神經(jīng)網(wǎng)絡(luò),用于研究神經(jīng)信號傳導和神經(jīng)疾病機制。
Neuronal cells cultured in Matrigel can form complex neural networks, used to study neural signal transmission and the mechanisms of neurological diseases.